To our community: Due to circumstances surrounding COVID-19, Clinical Research IO had to make the difficult decision to discontinue funding for Caretalk. We've decided to leave the website up as a resource for the community. Thank you so much to everyone who made this possible, and please enjoy!

Treatments for
Type 2 Diabetes

Reviewed by Nicholas Yozamp, MD, Washington University in St. Louis

A variety of treatments exist for Type 2 Diabetes. Usually, treament options include changes in diet and exercise, and medications, such as oral medications or supplemental insulin. Medications can help restore your insulin levels or help your cells better detect insulin. You may be also instructed to track your blood sugar levels.



Don't Know Where to Start?
Explore Your Medication Options

(For example, Metformin, Acarbose, or insulin)

Explore Your Device Options

(For example, blood glucose monitors or insulin pumps)

Compare & Treatments

Alpha-glucosidase inhibitors

Compare Name Manufacturer
How To Take It
Type
Cost Follow
Precose (Acarbose) Bayer HealthCare Pharmaceuticals By Mouth (Tablet) Alpha-glucosidase inhibitors $91.64
Glyset (Miglitol) Bayer HealthCare Pharmaceuticals By Mouth (Tablet) Alpha-glucosidase inhibitors $180.79

Biguanides

Compare Name Manufacturer How To Take It Type Cost Follow
Glucophage (Metformin) Bristol-Myers Squibb By Mouth (Tablet) Biguanides $26.90
Glucophage XR (Metformin) Bristol-Myers Squibb By Mouth (Tablet) Biguanides $26.90
Fortamet (Metformin) Andrx Labs, Inc. By Mouth (Tablet) Biguanides $26.90
Glumetza (Metformin) Biovail Laboratories Inc. By Mouth (Tablet) Biguanides $26.90
Riomet (Metformin) Biovail Laboratories Inc. By Mouth (Liquid) Biguanides $26.90

Bile Acid Sequestrants (BASs)*

Compare Name Manufacturer How To Take It Type Cost Follow
Welchol (Colesevelam) Daiichi Sankyo By Mouth (Tablet) Bile Acid Sequestrants (BASs)* $600.97

Dopamine-2 Agonists*

Compare Name Manufacturer How To Take It Type Cost Follow
Cycloset (Bromocriptine) VeroScience By Mouth (Tablet) Dopamine-2 Agonists*

DPP-4 Inhibitors

Compare Name Manufacturer How To Take It Type Cost Follow
Nesina (Alogliptin) Takeda Pharmaceuticals North America, Inc. By Mouth (Tablet) DPP-4 Inhibitors $237.22
Tradjenta (Linagliptin) Boehringer Ingelheim Pharmaceuticals By Mouth (Tablet) DPP-4 Inhibitors $523.78
Onglyza (Saxagliptin) Bristol-Myers Squibb By Mouth (Tablet) DPP-4 Inhibitors $534.96
Januvia (Sitagliptin) Merck & Co., Inc. By Mouth (Tablet) DPP-4 Inhibitors $570.60

Meglitinides

Compare Name Manufacturer How To Take It Type Cost Follow
Starlix (Nateglinide) Novartis Pharmaceuticals Corp By Mouth (Tablet) Meglitinides $162.94
Prandin (Repaglinide) Novo Nordisk By Mouth (Tablet) Meglitinides $291.88

SGLT2 Inhibitors

Compare Name Manufacturer How To Take It Type Cost Follow
Invokana (Canagliflozin) Janssen Pharmaceuticals, Inc. By Mouth (Tablet) SGLT2 Inhibitors $628.28
Farxiga (Dapagliflozin) Astrazeneca Pharmaceuticals By Mouth (Tablet) SGLT2 Inhibitors $636.47
Jardiance (Empagliflozin) Boehringer Ingelheim and Eli Lilly By Mouth (Tablet) SGLT2 Inhibitors $604.03

Sulfonylureas

Compare Name Manufacturer How To Take It Type Cost Follow
Amaryl (Glimepiride) Sanofi Pasteur, Inc. By Mouth (Tablet) Sulfonylureas $59.76
Glucotrol (Glipizide) Pfizer Inc. By Mouth (Tablet) Sulfonylureas $20.89
Glucotrol XL (Glipizide) Pfizer Inc. By Mouth (Tablet) Sulfonylureas $27.60
Micronase (Glyburide) By Mouth (Tablet) Sulfonylureas $32.73
Glynase (Glyburide) Pfizer Inc. By Mouth (Tablet) Sulfonylureas $38.82
Diabeta (Glyburide) Sanofi Pasteur, Inc. By Mouth (Tablet) Sulfonylureas
(Tolazamide) By Mouth (Tablet) Sulfonylureas
(Tolbutamide) By Mouth (Tablet) Sulfonylureas

Thiazolidinediones (TZDs)

Compare Name Manufacturer How To Take It Type Cost Follow
Avandia (Rosiglitazone) GlaxoSmithKline (GSK) By Mouth (Tablet) Thiazolidinediones (TZDs) $208.29
Actos (Pioglitazone) Takeda Pharmaceuticals North America, Inc. By Mouth (Tablet) Thiazolidinediones (TZDs) $138.70

GLP-1 Receptor Agonists

Compare Name Manufacturer How To Take It Type Cost Follow
Byetta (Exenatide) Astrazeneca Pharmaceuticals Injection GLP-1 Receptor Agonists
Bydureon (Exenatide) Astrazeneca Pharmaceuticals Injection GLP-1 Receptor Agonists
Trulicity (Dulaglutide) Eli Lilly and Company Injection GLP-1 Receptor Agonists
Victoza (Liraglutide) Novo Nordisk Injection GLP-1 Receptor Agonists

Amylin Analog

Compare Name Manufacturer How To Take It Type Cost Follow
Symlin (Pramlintide Acetate) Astrazeneca Pharmaceuticals Injection Amylin Analog

Oral Combination Medications

Compare Name Manufacturer How To Take It Type Cost Follow
ActoPlus Met (Pioglitazone / Metformin) Takeda Pharmaceuticals North America, Inc. By Mouth (Tablet) Oral Combination Medications $310.72
ActoPlus Met XR (Pioglitazone / Metformin) Takeda Pharmaceuticals North America, Inc. By Mouth (Tablet) Oral Combination Medications
Duetact (Pioglitazone / Glimepiride) Takeda Pharmaceuticals North America, Inc. By Mouth (Tablet) Oral Combination Medications $451.75
Glucovance (Glyburide / Metformin) Bristol-Myers Squibb By Mouth (Tablet) Oral Combination Medications $88.78
Janumet (Sitagliptin and Metformin) Merck & Co., Inc. By Mouth (Tablet) Oral Combination Medications $581.52
Janumet XR (Sitagliptin and Metformin) Merck & Co., Inc. By Mouth (Tablet) Oral Combination Medications $574.14
Jentadueto (Linagliptin and Metformin) Boehringer Ingelheim and Eli Lilly By Mouth (Tablet) Oral Combination Medications $547.72
Kazano (Alogliptin and Metformin) Takeda Pharmaceuticals North America, Inc. By Mouth (Tablet) Oral Combination Medications $300.97
Kombiglyze XR (Saxagliptin and Metformin) Astrazeneca Pharmaceuticals By Mouth (Tablet) Oral Combination Medications $497.76
Metaglip (Glipizide and Metformin) Bristol-Myers Squibb By Mouth (Tablet) Oral Combination Medications $52.44
Oseni (Alogliptin and Pioglitazone) Takeda Pharmaceuticals North America, Inc. By Mouth (Tablet) Oral Combination Medications $240.55
Xigduo XR (Dapagliflozin and Metformin) Astrazeneca Pharmaceuticals By Mouth (Tablet) Oral Combination Medications $603.38
Invokamet (Canagliflozin and Metformin) Janssen Pharmaceuticals, Inc. By Mouth (Tablet) Oral Combination Medications $629.07

Rapid-acting Insulin

Compare Name Manufacturer How To Take It Type Cost Follow
Admelog (Insulin lispro) Sanofi Pasteur, Inc. Injection Rapid-acting Insulin
Humalog (Insulin lispro) Eli Lilly and Company Injection Rapid-acting Insulin
Apidra (Insulin glulisine) Sanofi Pasteur, Inc. Injection Rapid-acting Insulin
Fiasp (Insulin aspart) Novo Nordisk Injection Rapid-acting Insulin
NovoLog (Insulin aspart) Novo Nordisk Injection Rapid-acting Insulin
Afrezza (Insulin human) MannKind Corporation Inhalation Rapid-acting Insulin

Regular-acting insulin

Compare Name Manufacturer How To Take It Type Cost Follow
Humulin R (Human Regular) Eli Lilly and Company Injection Regular-acting insulin
Novolin R (Human Regular) Novo Nordisk Injection Regular-acting insulin

Intermediate-acting insulin

Compare Name Manufacturer How To Take It Type Cost Follow
Humulin N (NPH (Neutral Protamine Hagedorn) Insulin) Eli Lilly and Company Injection Intermediate-acting insulin
Novolin N (NPH (Neutral Protamine Hagedorn) Insulin) Novo Nordisk Injection Intermediate-acting insulin

long-acting insulin

Compare Name Manufacturer How To Take It Type Cost Follow
Tresiba (Degludec insuiln) Novo Nordisk Injection long-acting insulin
Levemir (Detemir insulin) Novo Nordisk Injection long-acting insulin
Basaglar (Insulin glargine) Eli Lilly and Company Injection long-acting insulin
Lantus (Insulin glargine) Sanofi Pasteur, Inc. Injection long-acting insulin

Ultra long-acting insulin

Compare Name Manufacturer How To Take It Type Cost Follow
Toujeo (Insulin glargine) Sanofi Pasteur, Inc. Injection Ultra long-acting insulin

Insulin Mixes

Compare Name Manufacturer How To Take It Type Cost Follow
Humalog Mix 50/50 (Insulin lispro protamine (intermediate-acting) (50%) and insulin lispro (rapid-acting) (50%)) Eli Lilly and Company Injection Insulin Mixes
Humalog Mix 75/25 (Insulin lispro protamine (intermediate-acting) (75%) and insulin lispro (rapid-acting) (25%)) Eli Lilly and Company Injection Insulin Mixes
Humulin 70/30 (Human insulin isophane suspension (70%) and human insulin injection (30%)) Eli Lilly and Company Injection Insulin Mixes
NovoLog Mix 70/30 (Insulin aspart protoamine suspension (70%) and insulin aspart injection (30%)) Novo Nordisk Injection Insulin Mixes
Novolin 70/30 (Human insulin isophane suspension (70%) and human insulin injection (30%)) Novo Nordisk Injection Insulin Mixes
Soliqua 100/33 (Insulin glargine (U-100 long-acting insulin) (specifically, the brand Lantus) and lixisenatide (not insulin, but a GLP-1 receptor agonist)) Sanofi Pasteur, Inc. Injection Insulin Mixes
Xultophy 100/3.6 (Insulin degludec (Tresiba brand) and liraglutide (not insulin, but a GLP-1 receptor agonist -- specifically, Victoza brand)) Novo Nordisk Injection Insulin Mixes

Insulin Delivery

Compare Name Manufacturer How To Take It Type Cost Follow
Insulin Syringes & Vials (Assorted) Many. Syringe Insulin Delivery <$40 for 100 syringes
Tresiba Flextouch U-100 (Insulin degludec) Novo Nordisk Pen Insulin Delivery
Tresiba Flextouch U-200 (Insulin degludec) Novo Nordisk Pen Insulin Delivery
Fiasp Flextouch (Insulin aspart injection) Novo Nordisk Pen Insulin Delivery
Levemir Flextouch (Insulin detemir) Novo Nordisk Pen Insulin Delivery
Novolog Flexpen (Insulin aspart injection) Novo Nordisk Pen Insulin Delivery
Novopen Echo ( ) Novo Nordisk Pen Insulin Delivery
Admelog SoloStar (Insulin lispro) Sanofi Pen Insulin Delivery
Apidra SoloStar (Insulin Glulisine) Sanofi Pen Insulin Delivery
Lantus SoloStar (Insulin glargine) Sanofi Pen Insulin Delivery
Toujeo SoloStar Pen (Insulin glargine) Sanofi Pen Insulin Delivery
Toujeo Max SoloStar Pen (Insulin glargine) Sanofi Pen Insulin Delivery
Autopen Classic (21 units per injection) Owen Mumford Pen Insulin Delivery
Autopen Classic (42 units per injection) Owen Mumford Pen Insulin Delivery
Basaglar KwikPen (Insulin glargine) Eli Lilly Pen Insulin Delivery
Humalog KwikPen (Insulin lispro) Eli Lilly Pen Insulin Delivery
Humalog KwikPen U-200 (Insulin lispro) Eli Lilly Pen Insulin Delivery
Humulin KwikPen - Humulin N and Humulin 70/30 (Isophane insulin) Eli Lilly Pen Insulin Delivery
Humulin KwikPen - Humulin R U-500 (Isophane insulin) Eli Lilly Pen Insulin Delivery
InPen System () Companion Medical, Inc. Pen Insulin Delivery
Omnipod () Insulet Corporation Pump Insulin Delivery
MiniMed 630G Pump () Medtronic Diabetes Pump Insulin Delivery
T:slim X2 Pump () Tandem Diabetes Care Pump Insulin Delivery
V-Go (Patch Pump) Valeritas Pump Insulin Delivery $465.58

Monitoring Blood Glucose

Compare Name Manufacturer How To Take It Type Cost Follow
Freestyle Freedom Lite () Abbott Diabetes Care Meter Monitoring Blood Glucose
Contour Next () Ascensia Diabetes Care Meter Monitoring Blood Glucose
True Metrix Blood Glucose Meter () Nipro Diagnostics, Inc. Meter Monitoring Blood Glucose
Accu-Chek Aviva Plus () Roche Meter Monitoring Blood Glucose
Freestyle Lite () Abbot Diabetes Care Meter Monitoring Blood Glucose
Contour Next EZ Meter () Ascensia Diabetes Care Meter Monitoring Blood Glucose
GE 100 () Bionime Corporation Meter Monitoring Blood Glucose
CareTouch Blood Glucose Meter () CareTouch Meter Monitoring Blood Glucose
Keto-Mojo Blood Ketone and Glucose Testing Kit () Meter Monitoring Blood Glucose
On Call Express Blood Glucose Meter () Acon Laboratories, Inc. Meter Monitoring Blood Glucose
FreeStyle Libre 14-Day System () Abbott CGM Monitoring Blood Glucose
Dexcom G6 () Dexcom, Inc. CGM Monitoring Blood Glucose
Dexcom G5 Mobile System () Dexcom CGM Monitoring Blood Glucose
Guardian Connect Smart CGM (with Medtronic Guardian Sensor 3) () Medtronic MiniMed Inc. CGM Monitoring Blood Glucose
Senseonics Eversense CGM System () Senseonics, Inc. CGM Monitoring Blood Glucose

Insulin pumps

Compare Name Manufacturer How To Take It Type Cost Follow
Minimed 670G Medtronic Pump Insulin pumps

Treatment Requests from the Community

What does this mean?

Caretalk is created by you, a community of experts, patients, caregivers, and advocates of Type 2 Diabetes. So, if you wish another treatment was on Caretalk, simply vote for one below or suggest another. If you are a clinical expert, fill in the treatment information to get attributed as the First Author. Once it's filled in, the community will be notified!

Want to help find the next diabetes treatment?

You can help bring everyone closer to a cure. Learn why clinical research matters and how you can get involved today!

Get Involved

Related Articles