To our community: Due to circumstances surrounding CONVID-19, Clinical Research IO had to make the difficult decision to discontinue funding for Caretalk. We've decided to leave the website up as a resource for the community. Thank you so much to everyone who made this possible, and please enjoy!

What is Clinical Research?

Reviewed by Sowmya Chary, MD, MMSc(c) - Sri Ramachandra Institute of Higher Education and Research, Harvard Medical School

Clinical trials are one of the cornerstones of medical innovation in Type 2 Diabetes. Almost all of the treatments we rely on today were tested in trials, and there are tens of thousands of clinical trials--testing the treatments of tomorrow--going on right now. Keep scrolling to learn more about this process or find trials near you.

The Stages of Clinical Research

Phase 1

Phase 1 (or "first-in-human") trials study the safety and toxicity of a new intervention. The participants are often healthy volunteers, rather than patients.

Phase 2

Phase 2 trials are the first tests of an experimental treatment's efficacy against a particular disease or condition. The participants are usually patients who do not benefit from the available therapies.

Phase 3

Phase 3 (or "pivotal") trials are the decisive tests that regulators use to decide if a treatment should be approved for general use. These studies usually randomize patients to receive either the experimental treatment or a control treatment, like a placebo or a medication already approved to treat the condition.

Phase 4

Phase 4 (or "post-marketing") trials are conducted after a treatment has received regulatory approval. These are often very large studies that will focus on long-term safety and efficacy outcomes.

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