What is Clinical Research?
Reviewed by Sowmya Chary, MD, MMSc(c) - Sri Ramachandra Institute of Higher Education and Research, Harvard Medical School
Clinical trials are one of the cornerstones of medical innovation in Alzheimer's Disease. Almost all of the treatments we rely on today were tested in trials, and there are tens of thousands of clinical trials--testing the treatments of tomorrow--going on right now. Keep scrolling to learn more about this process or find trials near you.
The Stages of Clinical Research
Phase 1 (or "first-in-human") trials study the safety and toxicity of a new intervention. The participants are often healthy volunteers, rather than patients.
Phase 2 trials are the first tests of an experimental treatment's efficacy against a particular disease or condition. The participants are usually patients who do not benefit from the available therapies.
Phase 3 (or "pivotal") trials are the decisive tests that regulators use to decide if a treatment should be approved for general use. These studies usually randomize patients to receive either the experimental treatment or a control treatment, like a placebo or a medication already approved to treat the condition.
Phase 4 (or "post-marketing") trials are conducted after a treatment has received regulatory approval. These are often very large studies that will focus on long-term safety and efficacy outcomes.
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A few studies that could be a good fit
Clinical Performance of Reveal G4 Rapid HIV-1 Antibody Test for the Detection of HIV-1 Antibodies in Fingerstick and Venous Whole Blood SamplesLocated: Boston, MA Learn More
A 12-week, Multicenter, Active-treatment Extension Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's TypeLocated: Houston, TX | Beaumont, TX Learn More
A Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of AXS-05 for the Treatment of Agitation in Subjects With Dementia of the Alzheimer's TypeLocated: Houston, TX | Avon, IN | Banning, CA Learn More
A Randomized, Double-Blind, Placebo-Controlled and Delayed-Start Study of LY3314814 in Mild Alzheimer's Disease DementiaLocated: Tucson, AZ | Penticton, BC, MA | Clinton, UT | Avon, IN | Banning, CA | Raleigh, NC Learn More
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